|Movie|| The Amazing Spider-Man (mentioned)|
The Amazing Spider-Man 2
|Game|| The Amazing Spider-Man (mentioned) |
The Amazing Spider-Man 2 (mentioned)
- "This isn't how I imagined I'd die, looking at my son and seeing a stranger."
- —Norman Osborn[src]
Little is known of Norman Osborn, other than that he had a debilitating disease called 'Retroviral Hypodisplasia' which killed him. Dr. Curt Connors' and Dr. Rajit Ratha's experiments with lizard DNA were an attempt to cure him, until Connors used the serum on himself, transforming into the monstrous Lizard. After the Lizard was destroyed (for the first time), Connors and Ratha quit their works, and Connors was thrown into a mental institute. Currently, there are no known cures for Osborn's illness, and it is unknown if anyone is even attempting to cure him.
Norman's son Harry returns after years away and visits him in hospital, where by this point Norman is in very poor health. Norman explains to Harry that his illness is genetic, and that he is at the right age where it begins to show. Before he dies, Norman gives Harry a device saying it is his life's work. The next day, it is reported that Norman had passed away.
- Osborn, in other Spider-Man media, takes on the identity of the Green Goblin, a famous Spider-Man villain. However in this universe its his son Harry who first takes on the identity of the Green Goblin.
- Chris Cooper had stated that Norman's appearance in The Amazing Spider-Man 2 would be the introduction to the character, and a return in The Amazing Spider-Man 3 will be on the cards.