Beloit Psychiatric Hospital is an asylum built to hold patients from the mentally innocent to the dangerously insane. It also holds numerous criminals. Recently, Spider-Man broke into the asylum to free patient Curt Connors so he can stop the cross-species virus. However, this caused a prison riot and all of the inhabitants escaped. After all was said and done, Connors and the rest of the patients were returned to the institute by Spider-Man and the police.
- Beloit security guards (guards)
- Curtis Connors (prisoner, patient, temporarily escaped)
- Various insane criminals (prisoners, temporarily escaped)
- Various mental patients (patients, temporarily escaped)
- Felicia Hardy, escaped (prisoner, patient)